Cargando…

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress

Environmental insults such as oxidative stress can damage cell membranes. Lysosomes are particularly sensitive to membrane permeabilization since their function depends on intraluminal acidic pH and requires stable membrane-dependent proton gradients. Among the catalog of oxidative stress-responsive...

Descripción completa

Detalles Bibliográficos
Autores principales: Pascua-Maestro, Raquel, Diez-Hermano, Sergio, Lillo, Concepción, Ganfornina, Maria D., Sanchez, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325589/
https://www.ncbi.nlm.nih.gov/pubmed/28182653
http://dx.doi.org/10.1371/journal.pgen.1006603