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Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy
During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325604/ https://www.ncbi.nlm.nih.gov/pubmed/28192515 http://dx.doi.org/10.1371/journal.ppat.1006227 |