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Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy

During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circ...

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Detalles Bibliográficos
Autores principales:	Ganesan, Raja, Hos, Nina Judith, Gutierrez, Saray, Fischer, Julia, Stepek, Joanna Magdalena, Daglidu, Evmorphia, Krönke, Martin, Robinson, Nirmal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325604/ https://www.ncbi.nlm.nih.gov/pubmed/28192515 http://dx.doi.org/10.1371/journal.ppat.1006227

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