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Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

Mucins are heavily glycosylated proteins that give mucus its gel-like properties. Moreover, the glycans decorating the mucin protein core can alter the protective properties of the mucus barrier. To investigate whether these alterations could be parasite-induced we utilized the Trichuris muris (T. m...

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Detalles Bibliográficos
Autores principales: Hasnain, Sumaira Z., Dawson, Paul A., Lourie, Rohan, Hutson, Peter, Tong, Hui, Grencis, Richard K., McGuckin, Michael A., Thornton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325613/
https://www.ncbi.nlm.nih.gov/pubmed/28192541
http://dx.doi.org/10.1371/journal.ppat.1006218