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Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence
PURPOSE: The Nijmegen breakage syndrome (NBS) is an inherited genetic disorder characterized by a typical facial appearance, microcephaly, growth retardation, immunodeficiency, and a strong predisposition to malignancies, especially of lymphoid origin. NBS patients have a mutation in the NBN gene wh...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325864/ https://www.ncbi.nlm.nih.gov/pubmed/28000062 http://dx.doi.org/10.1007/s10875-016-0363-5 |