Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence

PURPOSE: The Nijmegen breakage syndrome (NBS) is an inherited genetic disorder characterized by a typical facial appearance, microcephaly, growth retardation, immunodeficiency, and a strong predisposition to malignancies, especially of lymphoid origin. NBS patients have a mutation in the NBN gene wh...

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Detalles Bibliográficos
Autores principales: Meijers, Ruud W. J., Dzierzanowska-Fangrat, Katarzyna, Zborowska, Magdalena, Solarska, Iwona, Tielemans, Dennis, van Turnhout, Bob A. C., Driessen, Gertjan, van der Burg, Mirjam, van Dongen, Jacques J. M., Chrzanowska, Krystyna H., Langerak, Anton W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325864/
https://www.ncbi.nlm.nih.gov/pubmed/28000062
http://dx.doi.org/10.1007/s10875-016-0363-5

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