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In silico prediction of B cell epitopes of the extracellular domain of insulin-like growth factor-1 receptor

The insulin-like growth factor-1 receptor (IGF-1R) is a transmembrane receptor with tyrosine kinase activity. The receptor plays a critical role in cancer. Using monoclonal antibodies (MAbs) against the IGF-1R, typically blocks ligand binding and enhances down-regulation of the cell-surface IGF-1R....

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Detalles Bibliográficos
Autores principales: Bayrami, Vahid, Keyhanfar, Mehrnaz, Mohabatkar, Hassan, Mahdavi, Manijeh, Moreau, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326484/
https://www.ncbi.nlm.nih.gov/pubmed/28261624