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In silico prediction of B cell epitopes of the extracellular domain of insulin-like growth factor-1 receptor
The insulin-like growth factor-1 receptor (IGF-1R) is a transmembrane receptor with tyrosine kinase activity. The receptor plays a critical role in cancer. Using monoclonal antibodies (MAbs) against the IGF-1R, typically blocks ligand binding and enhances down-regulation of the cell-surface IGF-1R....
Autores principales: | Bayrami, Vahid, Keyhanfar, Mehrnaz, Mohabatkar, Hassan, Mahdavi, Manijeh, Moreau, Violaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326484/ https://www.ncbi.nlm.nih.gov/pubmed/28261624 |
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