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Influence of heparin molecular size on the induction of C- terminal unfolding in β2-microglobulin

Dialysis-related amyloidosis (DRA) is characterized by accumulation of amyloid β2- microglobulin (β2m) in the interstitial matrix. Matrix substances such as heparin have reportedly been strongly implicated in the pathogenesis of dialysis-related amyloidosis. In clinical setting of hemodialysis, two...

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Detalles Bibliográficos
Autores principales: Fukasawa, Kanon, Higashimoto, Yuichiro, Motomiya, Yoshihiro, Uji, Yoshinori, Ando, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326486/
https://www.ncbi.nlm.nih.gov/pubmed/28261626