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Expression of SOCS1 and the downstream targets of its putative tumor suppressor functions in prostate cancer

BACKGROUND: Suppressor of cytokine signaling 1 (SOCS1) is considered a tumor suppressor due to frequent epigenetic and micro-RNA-mediated repression of its gene expression in diverse cancers. In prostate cancer (PCa), elevated expression of miR-30d that targets SOCS1 mRNA is associated with increase...

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Detalles Bibliográficos
Autores principales: Chevrier, Martin, Bobbala, Diwakar, Villalobos-Hernandez, Alberto, Khan, Md Gulam Musawwir, Ramanathan, Sheela, Saucier, Caroline, Ferbeyre, Gerardo, Geha, Sameh, Ilangumaran, Subburaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326496/
https://www.ncbi.nlm.nih.gov/pubmed/28235401
http://dx.doi.org/10.1186/s12885-017-3141-8