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Inhibition of calcineurin by FK506 stimulates germinal vesicle breakdown of mouse oocytes in hypoxanthine-supplemented medium

Calcineurin (CN) is a serine/threonine phosphatase which plays important roles in meiosis maturation in invertebrate oocytes; however, the role of CN in mouse oocytes is relatively unexplored. In this study, we examined the expression, localization and functional roles of CN in mouse oocytes and gra...

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Detalles Bibliográficos
Autores principales: Wang, Li, Zhen, Yan-Hong, Liu, Xiao-Ming, Cao, Jing, Wang, Yan-Ling, Huo, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326542/
https://www.ncbi.nlm.nih.gov/pubmed/28243539
http://dx.doi.org/10.7717/peerj.3032