E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain

UHRF2 is a ubiquitin-protein ligase E3 that regulates cell cycle, genomic stability and epigenetics. We conducted a co-immunoprecipitation assay and found that TIP60 and HDAC1 interact with UHRF2. We previously demonstrated that UHRF2 regulated H3K9ac and H3K14ac differentially in normal and cancer...

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Detalles Bibliográficos
Autores principales: Zeng, Shengyuan, Wang, Yangyang, Zhang, Ting, Bai, Lu, Wang, Yalan, Duan, Changzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326618/
https://www.ncbi.nlm.nih.gov/pubmed/27743347
http://dx.doi.org/10.1007/s13238-016-0324-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326618/
https://www.ncbi.nlm.nih.gov/pubmed/27743347
http://dx.doi.org/10.1007/s13238-016-0324-z

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