Specific and Efficient Uptake of Surfactant-Free Poly(Lactic Acid) Nanovaccine Vehicles by Mucosal Dendritic Cells in Adult Zebrafish after Bath Immersion

Activation of mucosal immunity is a key milestone for next-generation vaccine development. Biocompatible polymer-based nanoparticles (NPs) are promising vectors and adjuvants for mucosal vaccination. However, their in vivo uptake by mucosae and their biodistribution in antigen-presenting cells (APCs...

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Detalles Bibliográficos
Autores principales: Rességuier, Julien, Delaune, Emilie, Coolen, Anne-Line, Levraud, Jean-Pierre, Boudinot, Pierre, Le Guellec, Dominique, Verrier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326745/
https://www.ncbi.nlm.nih.gov/pubmed/28289416
http://dx.doi.org/10.3389/fimmu.2017.00190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326745/
https://www.ncbi.nlm.nih.gov/pubmed/28289416
http://dx.doi.org/10.3389/fimmu.2017.00190

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