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Loss of Saltation and Presynaptic Action Potential Failure in Demyelinated Axons
In cortical pyramidal neurons the presynaptic terminals controlling transmitter release are located along unmyelinated axon collaterals, far from the original action potential (AP) initiation site, the axon initial segment (AIS). Once initiated, APs will need to reliably propagate over long distance...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326753/ https://www.ncbi.nlm.nih.gov/pubmed/28289377 http://dx.doi.org/10.3389/fncel.2017.00045 |