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White Matter Damage in the Cholinergic System Contributes to Cognitive Impairment in Subcortical Vascular Cognitive Impairment, No Dementia

Cholinergic deficiency has been implicated in the pathogenesis of vascular cognitive impairment (VCI), but the extent of involvement and underlying mechanism remain unclear. In this study, targeting the early stage of VCI, we determined regional atrophy within the basal forebrain and deficiency in c...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Zhu, Zude, Teipel, Stefan J., Yang, Jianwei, Xing, Yi, Tang, Yi, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326769/
https://www.ncbi.nlm.nih.gov/pubmed/28289381
http://dx.doi.org/10.3389/fnagi.2017.00047