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Effects of Histone Deacetylase Inhibitor (Valproic Acid) on the Expression of Hypoxia-inducible Factor-1 Alpha in Human Retinal Müller Cells

PURPOSE: To evaluate the effects of valproic acid (VPA), a histone deacetylase inhibitor (HDACI), on the expression of hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) in human retinal Müller cells under hypoxic conditions. METHODS: Chemical hypoxia was induced...

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Detalles Bibliográficos
Autores principales: Kim, Young Jun, Park, Sang Jun, Kim, Na Rae, Chin, Hee Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Ophthalmological Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327178/
https://www.ncbi.nlm.nih.gov/pubmed/28243027
http://dx.doi.org/10.3341/kjo.2017.31.1.80