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Influence of extracellular zinc on M1 microglial activation

Extracellular zinc, which is released from hippocampal neurons in response to brain ischaemia, triggers morphological changes in microglia. Under ischaemic conditions, microglia exhibit two opposite activation states (M1 and M2 activation), which may be further regulated by the microenvironment. We...

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Detalles Bibliográficos
Autores principales: Higashi, Youichirou, Aratake, Takaaki, Shimizu, Shogo, Shimizu, Takahiro, Nakamura, Kumiko, Tsuda, Masayuki, Yawata, Toshio, Ueba, Tetuya, Saito, Motoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327400/
https://www.ncbi.nlm.nih.gov/pubmed/28240322
http://dx.doi.org/10.1038/srep43778