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Influence of extracellular zinc on M1 microglial activation
Extracellular zinc, which is released from hippocampal neurons in response to brain ischaemia, triggers morphological changes in microglia. Under ischaemic conditions, microglia exhibit two opposite activation states (M1 and M2 activation), which may be further regulated by the microenvironment. We...
Autores principales: | Higashi, Youichirou, Aratake, Takaaki, Shimizu, Shogo, Shimizu, Takahiro, Nakamura, Kumiko, Tsuda, Masayuki, Yawata, Toshio, Ueba, Tetuya, Saito, Motoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327400/ https://www.ncbi.nlm.nih.gov/pubmed/28240322 http://dx.doi.org/10.1038/srep43778 |
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