Circulating cathepsin-S levels correlate with GFR decline and sTNFR1 and sTNFR2 levels in mice and humans

Cardiovascular complications determine morbidity/mortality in chronic kidney disease (CKD). We hypothesized that progressive CKD drives the release of cathepsin-S (Cat-S), a cysteine protease that promotes endothelial dysfunction and cardiovascular complications. Therefore, Cat-S, soluble tumor-necr...

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Detalles Bibliográficos
Autores principales: Steubl, Dominik, Kumar, Santhosh V., Tato, Maia, Mulay, Shrikant R., Larsson, Anders, Lind, Lars, Risérus, Ulf, Renders, Lutz, Heemann, Uwe, Carlsson, Axel C., Ärnlöv, Johan, Anders, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327444/
https://www.ncbi.nlm.nih.gov/pubmed/28240259
http://dx.doi.org/10.1038/srep43538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327444/
https://www.ncbi.nlm.nih.gov/pubmed/28240259
http://dx.doi.org/10.1038/srep43538

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