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The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant
BACKGROUND: Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans. METHODS: Rapastinel was derived from a monoclonal antibody, B6...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327451/ https://www.ncbi.nlm.nih.gov/pubmed/26997507 http://dx.doi.org/10.2174/1570159X14666160321122703 |