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Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression

MmpL3 is an inner membrane transporter of Mycobacterium tuberculosis responsible for the export of trehalose momomycolate, a precursor of the mycobacterial outer membrane component trehalose dimycolate (TDM), as well as mycolic acids bound to arabinogalactan. MmpL3 represents an emerging target for...

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Detalles Bibliográficos
Autores principales: Degiacomi, Giulia, Benjak, Andrej, Madacki, Jan, Boldrin, Francesca, Provvedi, Roberta, Palù, Giorgio, Kordulakova, Jana, Cole, Stewart T., Manganelli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327466/
https://www.ncbi.nlm.nih.gov/pubmed/28240248
http://dx.doi.org/10.1038/srep43495