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Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
MmpL3 is an inner membrane transporter of Mycobacterium tuberculosis responsible for the export of trehalose momomycolate, a precursor of the mycobacterial outer membrane component trehalose dimycolate (TDM), as well as mycolic acids bound to arabinogalactan. MmpL3 represents an emerging target for...
Autores principales: | Degiacomi, Giulia, Benjak, Andrej, Madacki, Jan, Boldrin, Francesca, Provvedi, Roberta, Palù, Giorgio, Kordulakova, Jana, Cole, Stewart T., Manganelli, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327466/ https://www.ncbi.nlm.nih.gov/pubmed/28240248 http://dx.doi.org/10.1038/srep43495 |
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