Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia

β-thalassemia (βT) is a genetic blood disorder causing profound and life threatening anemia. Current clinical management of βT is a lifelong dependence on regular blood transfusions, a consequence of which is systemic iron overload leading to acute heart failure. Recent developments in gene and chel...

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Detalles Bibliográficos
Autores principales: Jackson, Laurence H., Vlachodimitropoulou, Evangelia, Shangaris, Panicos, Roberts, Thomas A., Ryan, Thomas M., Campbell-Washburn, Adrienne E., David, Anna L., Porter, John B., Lythgoe, Mark F., Stuckey, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327494/
https://www.ncbi.nlm.nih.gov/pubmed/28240317
http://dx.doi.org/10.1038/srep43439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327494/
https://www.ncbi.nlm.nih.gov/pubmed/28240317
http://dx.doi.org/10.1038/srep43439

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