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Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway

Sepsis-induced cardiac dysfunction remains a major cause of morbidity and mortality in patients suffered from severe trauma. Mesenchymal stem cells (MSCs) -based treatment has been verified as a promising approach to mitigate the sepsis-induced cardiac dysfunction, but the mechanism is still ambiguo...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Fan, Wensi, Wang, Yabin, Han, Dong, Li, Xiujuan, Li, Shuang, Li, Congye, Xu, Bin, Huang, Yuesheng, Fu, Xiaobin, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327616/
https://www.ncbi.nlm.nih.gov/pubmed/28250969
http://dx.doi.org/10.1038/cddiscovery.2016.97