Cargando…

Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity

The transmembrane four L6 family member 5 (TM4SF5) protein is a novel molecular target for the prevention and treatment of hepatocellular carcinoma. TM4SF5 is highly expressed in liver, colon, esophageal, and pancreatic cancers and is implicated in tumor progression. Here, we screened monoclonal ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Hye-Mi, Ryu, Jihye, Song, Jin Myeong, Lee, Yunhee, Kim, Hye-Jin, Ko, Dongjoon, Choi, Inpyo, Kim, Sang Jick, Lee, Jung Weon, Kim, Semi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327636/
https://www.ncbi.nlm.nih.gov/pubmed/28255353
http://dx.doi.org/10.7150/thno.15629