Cargando…
Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity
The transmembrane four L6 family member 5 (TM4SF5) protein is a novel molecular target for the prevention and treatment of hepatocellular carcinoma. TM4SF5 is highly expressed in liver, colon, esophageal, and pancreatic cancers and is implicated in tumor progression. Here, we screened monoclonal ant...
Autores principales: | Ahn, Hye-Mi, Ryu, Jihye, Song, Jin Myeong, Lee, Yunhee, Kim, Hye-Jin, Ko, Dongjoon, Choi, Inpyo, Kim, Sang Jick, Lee, Jung Weon, Kim, Semi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327636/ https://www.ncbi.nlm.nih.gov/pubmed/28255353 http://dx.doi.org/10.7150/thno.15629 |
Ejemplares similares
-
TM4SF5-Mediated Roles in the Development of Fibrotic Phenotypes
por: Ryu, Jihye, et al.
Publicado: (2017) -
Therapeutic effects of TM4SF5-targeting chimeric and humanized monoclonal antibodies in hepatocellular and colon cancer models
por: Ko, Dongjoon, et al.
Publicado: (2022) -
Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5
por: Kim, Semi, et al.
Publicado: (2014) -
TM4SF5-mediated liver malignancy involves NK cell exhaustion-like phenotypes
por: Sun, Hyunseung, et al.
Publicado: (2021) -
Correlations between Transmembrane 4 L6 Family Member 5 (TM4SF5), CD151, and CD63 in Liver Fibrotic Phenotypes and Hepatic Migration and Invasive Capacities
por: Kang, Minkyung, et al.
Publicado: (2014)