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STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) represents approximately 20% of all breast cancers and appears resistance to conventional cytotoxic chemotherapy, demonstrating a particularly poor prognosis and a significantly worse clinical outcome than other types of cancer. Suicide gene therapy has been used...

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Detalles Bibliográficos
Autores principales: Kuo, Wei-Ying, Hwu, Luen, Wu, Chun-Yi, Lee, Jhih-Shian, Chang, Chi-Wei, Liu, Ren-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327640/
https://www.ncbi.nlm.nih.gov/pubmed/28255357
http://dx.doi.org/10.7150/thno.16827