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Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD

Skeletal muscle atrophy and dysfunction are common complications in the chronic obstructive pulmonary disease (COPD). However, the underlying molecular mechanism remains elusive. Serum response factor (SRF) is a transcription factor which is critical in myocyte differentiation and growth. In this st...

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Detalles Bibliográficos
Autores principales: Ma, Ran, Gong, Xuefang, Jiang, Hua, Lin, Chunyi, Chen, Yuqin, Xu, Xiaoming, Zhang, Chenting, Wang, Jian, Lu, Wenju, Zhong, Nanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327903/
https://www.ncbi.nlm.nih.gov/pubmed/28260872
http://dx.doi.org/10.2147/COPD.S109243