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Preparation and antimicrobial evaluation of polyion complex (PIC) nanoparticles loaded with polymyxin B

Here, we describe novel polyion complex (PIC) particles for the delivery of Polymyxin B (Pol-B), an antimicrobial peptide currently used in the clinic as a last resort antibiotic against multidrug-resistant gram-negative bacteria. A range of conditions for the controlled assembly of Pol-B with poly(...

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Detalles Bibliográficos
Autores principales: Insua, Ignacio, Majok, Sieta, Peacock, Anna F.A., Krachler, Anne Marie, Fernandez-Trillo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327956/
https://www.ncbi.nlm.nih.gov/pubmed/28280277
http://dx.doi.org/10.1016/j.eurpolymj.2016.08.023