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Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B)

BACKGROUND: The objective of the present study was to identify the association between miR-15a-5p and CDKN2B, and their roles in regulating the development of abdominal aortic aneurysm (AAA). MATERIAL/METHODS: We searched the miRNA database online (www.mirdb.org) and used a luciferase reporter assay...

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Detalles Bibliográficos
Autores principales: Gao, Peng, Si, Jiyuan, Yang, Bin, Yu, Jixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328202/
https://www.ncbi.nlm.nih.gov/pubmed/28214350
http://dx.doi.org/10.12659/MSM.898233