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Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate

Dexamphetamine (AMPH) is a psychostimulant drug that is used both recreationally and as medication for attention deficit hyperactivity disorder. Preclinical studies have demonstrated that repeated exposure to AMPH can induce damage to nerve terminals of dopamine (DA) neurons. We here assessed the un...

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Detalles Bibliográficos
Autores principales: Schrantee, Anouk, Tremoleda, Jordi L., Wylezinska-Arridge, Marzena, Bouet, Valentine, Hesseling, Peter, Meerhoff, Gideon F., de Bruin, Kora M., Koeleman, Jan, Freret, Thomas, Boulouard, Michel, Desfosses, Emilie, Galineau, Laurent, Gozzi, Alessandro, Dauphin, François, Gsell, Willy, Booij, Jan, Lucassen, Paul J., Reneman, Liesbeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328278/
https://www.ncbi.nlm.nih.gov/pubmed/28241065
http://dx.doi.org/10.1371/journal.pone.0172776