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Neurochemical and motor changes in mice with combined mutations linked to Parkinson’s disease

Considerable evidence suggests that oxidative stress plays a role in the pathogenesis of Parkinson’s disease (PD), the most prevalent neurodegenerative movement disorder. Reduced expression of aldehyde dehydrogenase-1 (ALDH1) and glutathione peroxidase-1 (GPX1), enzymes that function to detoxify ald...

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Detalles Bibliográficos
Autores principales: Bai, Xiang, Wey, Margaret Chia-Ying, Martinez, Paul Anthony, Shi, Chao, Fernandez, Elizabeth, Strong, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328310/
https://www.ncbi.nlm.nih.gov/pubmed/28326165
http://dx.doi.org/10.1080/20010001.2017.1267855