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Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells

Chromosomal region 17q12-q21 is associated with asthma and harbors regulatory polymorphisms that influence expression levels of all five protein-coding genes in the region: IKAROS family zinc finger 3 (Aiolos) (IKZF3), zona pellucida binding protein 2 (ZPBP2), ORMDL sphingolipid biosynthesis regulat...

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Detalles Bibliográficos
Autores principales: Moussette, Sanny, Al Tuwaijri, Abeer, Kohan-Ghadr, Hamid-Reza, Elzein, Samar, Farias, Raquel, Bérubé, Julie, Ho, Bianca, Laprise, Catherine, Goodyer, Cynthia G., Rousseau, Simon, Naumova, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328393/
https://www.ncbi.nlm.nih.gov/pubmed/28241063
http://dx.doi.org/10.1371/journal.pone.0172707