SseK1 and SseK3 Type III Secretion System Effectors Inhibit NF-κB Signaling and Necroptotic Cell Death in Salmonella-Infected Macrophages

Within host cells such as macrophages, Salmonella enterica translocates virulence (effector) proteins across its vacuolar membrane via the SPI-2 type III secretion system. Previously, it was shown that when expressed ectopically, the effectors SseK1 and SseK3 inhibit tumor necrosis factor alpha (TNF...

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Detalles Bibliográficos
Autores principales: Günster, Regina A., Matthews, Sophie A., Holden, David W., Thurston, Teresa L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328493/
https://www.ncbi.nlm.nih.gov/pubmed/28069818
http://dx.doi.org/10.1128/IAI.00010-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328493/
https://www.ncbi.nlm.nih.gov/pubmed/28069818
http://dx.doi.org/10.1128/IAI.00010-17

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