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A Multistrain Mathematical Model To Investigate the Role of Pyrazinamide in the Emergence of Extensively Drug-Resistant Tuberculosis

Several infectious diseases of global importance—e.g., HIV infection and tuberculosis (TB)—require prolonged treatment with combination antimicrobial regimens typically involving high-potency core agents coupled with additional companion drugs that protect against the de novo emergence of mutations...

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Detalles Bibliográficos
Autores principales: Fofana, Mariam O., Shrestha, Sourya, Knight, Gwenan M., Cohen, Ted, White, Richard G., Cobelens, Frank, Dowdy, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328532/
https://www.ncbi.nlm.nih.gov/pubmed/27956422
http://dx.doi.org/10.1128/AAC.00498-16