SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies

SCY-078 is an orally bioavailable ß-1,3-glucan synthesis inhibitor (GSI) and the first-in-class of structurally novel triterpene antifungals in clinical development for treating candidemia and invasive candidiasis. In vitro susceptibilities by broth microdilution, antifungal carryover, and time-kill...

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Detalles Bibliográficos
Autores principales: Scorneaux, Bernard, Angulo, David, Borroto-Esoda, Katyna, Ghannoum, Mahmoud, Peel, Michael, Wring, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328566/
https://www.ncbi.nlm.nih.gov/pubmed/28069658
http://dx.doi.org/10.1128/AAC.01961-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328566/
https://www.ncbi.nlm.nih.gov/pubmed/28069658
http://dx.doi.org/10.1128/AAC.01961-16

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