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Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance
Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resista...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Diabetes Association
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328691/ https://www.ncbi.nlm.nih.gov/pubmed/28236381 http://dx.doi.org/10.4093/dmj.2017.41.1.10 |