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Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance

Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resista...

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Detalles Bibliográficos
Autor principal: Lee, Jae Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328691/
https://www.ncbi.nlm.nih.gov/pubmed/28236381
http://dx.doi.org/10.4093/dmj.2017.41.1.10