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Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast

The World Health Organization designates lidocaine as an essential medicine in healthcare, greatly increasing the probability of human exposure. Its use has been associated with ROS generation and neurotoxicity. Physiological and metabolomic alterations, and genetics leading to the clinically observ...

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Detalles Bibliográficos
Autores principales: Boone, Cory H.T., Grove, Ryan A., Adamcova, Dana, Seravalli, Javier, Adamec, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328717/
https://www.ncbi.nlm.nih.gov/pubmed/28236766
http://dx.doi.org/10.1016/j.redox.2017.01.025