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Triggering autophagic cell death with a di-manganese(II) developmental therapeutic
There is an unmet need for novel metal-based chemotherapeutics with alternative modes of action compared to clinical agents such as cisplatin and metallo-bleomycin. Recent attention in this field has focused on designing intracellular ROS-mediators as powerful cytotoxins of human cancers and identif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328722/ https://www.ncbi.nlm.nih.gov/pubmed/28236767 http://dx.doi.org/10.1016/j.redox.2017.01.024 |