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Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes

OBJECTIVE: To determine whether differentially methylated CpGs in synovium‐derived fibroblast‐like synoviocytes (FLS) of patients with rheumatoid arthritis (RA) were also differentially methylated in RA peripheral blood (PB) samples. METHODS: For this study, 371 genome‐wide DNA methylation profiles...

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Detalles Bibliográficos
Autores principales: Rhead, Brooke, Holingue, Calliope, Cole, Michael, Shao, Xiaorong, Quach, Hong L., Quach, Diana, Shah, Khooshbu, Sinclair, Elizabeth, Graf, John, Link, Thomas, Harrison, Ruby, Rahmani, Elior, Halperin, Eran, Wang, Wei, Firestein, Gary S., Barcellos, Lisa F., Criswell, Lindsey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328845/
https://www.ncbi.nlm.nih.gov/pubmed/27723282
http://dx.doi.org/10.1002/art.39952