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Sonic Hedgehog Signaling in Limb Development

The gene encoding the secreted protein Sonic hedgehog (Shh) is expressed in the polarizing region (or zone of polarizing activity), a small group of mesenchyme cells at the posterior margin of the vertebrate limb bud. Detailed analyses have revealed that Shh has the properties of the long sought aft...

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Detalles Bibliográficos
Autores principales: Tickle, Cheryll, Towers, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328949/
https://www.ncbi.nlm.nih.gov/pubmed/28293554
http://dx.doi.org/10.3389/fcell.2017.00014