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Sonic Hedgehog Signaling in Limb Development
The gene encoding the secreted protein Sonic hedgehog (Shh) is expressed in the polarizing region (or zone of polarizing activity), a small group of mesenchyme cells at the posterior margin of the vertebrate limb bud. Detailed analyses have revealed that Shh has the properties of the long sought aft...
Autores principales: | Tickle, Cheryll, Towers, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328949/ https://www.ncbi.nlm.nih.gov/pubmed/28293554 http://dx.doi.org/10.3389/fcell.2017.00014 |
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