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MLKL Mediated Necroptosis Accelerates JEV-Induced Neuroinflammation in Mice

Japanese encephalitis virus (JEV) is the most prevalent cause of viral encephalitis in Asia and the western Pacific. Neuronal death caused by JEV infection and inflammation induced cytotoxicity leads to progression and deterioration of Japanese encephalitis (JE). Mixed-lineage kinase domain-like pro...

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Detalles Bibliográficos
Autores principales: Bian, Peiyu, Zheng, Xuyang, Wei, Li, Ye, Chuantao, Fan, Hong, Cai, Yanhui, Zhang, Ying, Zhang, Fanglin, Jia, Zhansheng, Lei, Yingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328978/
https://www.ncbi.nlm.nih.gov/pubmed/28293227
http://dx.doi.org/10.3389/fmicb.2017.00303