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DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4(+)IL-10(+) Regulatory T Cells during Plasmodium yoelii Infection

The cytokine IL-10 plays a crucial role during malaria infection by counteracting the pro-inflammatory immune response. We and others demonstrated that Plasmodium yoelii infection results in enhanced IL-10 production in CD4(+) T cells accompanied by the induction of an immunosuppressive phenotype. H...

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Detalles Bibliográficos
Autores principales: Loevenich, Katharina, Ueffing, Kristina, Abel, Simone, Hose, Matthias, Matuschewski, Kai, Westendorf, Astrid M., Buer, Jan, Hansen, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328999/
https://www.ncbi.nlm.nih.gov/pubmed/28293237
http://dx.doi.org/10.3389/fimmu.2017.00152