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DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4(+)IL-10(+) Regulatory T Cells during Plasmodium yoelii Infection
The cytokine IL-10 plays a crucial role during malaria infection by counteracting the pro-inflammatory immune response. We and others demonstrated that Plasmodium yoelii infection results in enhanced IL-10 production in CD4(+) T cells accompanied by the induction of an immunosuppressive phenotype. H...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328999/ https://www.ncbi.nlm.nih.gov/pubmed/28293237 http://dx.doi.org/10.3389/fimmu.2017.00152 |