Cargando…

Neddylated Cullin 3 is required for vascular endothelial‐cadherin‐mediated endothelial barrier function

Vascular endothelial (VE)‐cadherin, a major endothelial adhesion molecule, regulates vascular permeability, and increased vascular permeability has been observed in several cancers. The aim of this study was to elucidate the role of the NEDD8‐Cullin E3 ligase, in maintaining barrier permeability. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakaue, Tomohisa, Fujisaki, Ayako, Nakayama, Hironao, Maekawa, Masashi, Hiyoshi, Hiromi, Kubota, Eiji, Joh, Takashi, Izutani, Hironori, Higashiyama, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329144/
https://www.ncbi.nlm.nih.gov/pubmed/27987332
http://dx.doi.org/10.1111/cas.13133