Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections

Altered neuregulin 1 (Nrg1)/ErbB signaling and glutamatergic hypofunction have been implicated in the pathophysiology of schizophrenia. Here, we employed gene chimeric ventral hippocampus (vHipp)-nucleus accumbens (nAcc) coculture from mouse, electrophysiology, immunocytochemistry, FM1-43 vesicle fu...

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Detalles Bibliográficos
Autores principales: Zhong, Chongbo, Akmentin, Wendy, Du, Chuang, Role, Lorna W., Talmage, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329619/
https://www.ncbi.nlm.nih.gov/pubmed/28275713
http://dx.doi.org/10.1523/ENEURO.0232-16.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329619/
https://www.ncbi.nlm.nih.gov/pubmed/28275713
http://dx.doi.org/10.1523/ENEURO.0232-16.2017

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