Epigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis

Acute myeloid leukaemia (AML) is a haematological malignancy characterized by clonal stem cell proliferation and aberrant block in differentiation. Dysfunction of epigenetic modifiers contributes significantly to the pathogenesis of AML. One frequently mutated gene involved in epigenetic modificatio...

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Detalles Bibliográficos
Autores principales: Chaudry, Sabah F., Chevassut, Timothy J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329657/
https://www.ncbi.nlm.nih.gov/pubmed/28286768
http://dx.doi.org/10.1155/2017/5473197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329657/
https://www.ncbi.nlm.nih.gov/pubmed/28286768
http://dx.doi.org/10.1155/2017/5473197

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