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Impact of T cells on hematopoietic stem and progenitor cell function: Good guys or bad guys?

When hematopoietic stem and progenitor cells (HSPC) are harvested for transplantation, either from the bone marrow or from mobilized blood, the graft contains a significant number of T cells. It is these T cells that are the major drivers of graft-vs-host disease (GvHD). The risk for GvHD can simply...

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Detalles Bibliográficos
Autores principales: Geerman, Sulima, Nolte, Martijn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329688/
https://www.ncbi.nlm.nih.gov/pubmed/28289507
http://dx.doi.org/10.4252/wjsc.v9.i2.37