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Impact of T cells on hematopoietic stem and progenitor cell function: Good guys or bad guys?
When hematopoietic stem and progenitor cells (HSPC) are harvested for transplantation, either from the bone marrow or from mobilized blood, the graft contains a significant number of T cells. It is these T cells that are the major drivers of graft-vs-host disease (GvHD). The risk for GvHD can simply...
Autores principales: | Geerman, Sulima, Nolte, Martijn A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329688/ https://www.ncbi.nlm.nih.gov/pubmed/28289507 http://dx.doi.org/10.4252/wjsc.v9.i2.37 |
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