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Retroviral integrase protein and intasome nucleoprotein complex structures

Retroviral replication proceeds through the integration of a DNA copy of the viral RNA genome into the host cellular genome, a process that is mediated by the viral integrase (IN) protein. IN catalyzes two distinct chemical reactions: 3’-processing, whereby the viral DNA is recessed by a di- or trin...

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Detalles Bibliográficos
Autores principales: Grawenhoff, Julia, Engelman, Alan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329712/
https://www.ncbi.nlm.nih.gov/pubmed/28289517
http://dx.doi.org/10.4331/wjbc.v8.i1.32